Luxury Hotels in Florence

We've selected 3 of the Best Luxury hotels in Florence for your 2026 vacation!

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Hilton Garden Inn Florence
2671 Hospitality Boulevard (6.7 km to City Center)
Howard Johnson By Wyndham Florence
2038 West Lucas Street (5.4 km to City Center)
Hotel Florence, Tapestry Collection By Hilton
126 West Evans Street (0.5 km to City Center)
Comfort Suites Florence I-95
2120 West Lucas Street (5.7 km to City Center)
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr By Ihg
3440 West Radio Drive (7.7 km to City Center)
Hampton Inn & Suites Florence Center
3000 West Radio Drive (6.9 km to City Center)

Top luxury hotels in Florence

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7.5
Very good
885 Reviews

From

109$/night

Comfort Suites Florence I-95

2120 West Lucas Street

Guests can take advantage of area shuttle offered by the smoke-free Comfort Suites Florence I-95 hotel, located 5 km from Florence Regional airport. Along with the use of an exercise room on site, sports fans are invited to discover Florence Civic Center Arena, which is about 7 km away.

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Luxury hotels in Florence with jacuzzi

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8.4
Very good
107 Reviews

From

149$/night

Hotel Florence, Tapestry Collection By Hilton

126 West Evans Street

Hotel Florence, Tapestry Collection By Hilton, located a 7-minute walk from First Baptist Church, features Wi-Fi in public areas.

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7.9
Very good
2548 Reviews

From

63$/night

Howard Johnson By Wyndham Florence

2038 West Lucas Street

Howard Johnson By Wyndham Florence hotel provides proximity to War Between the States Museum, which is situated 4.4 km away. The hotel features both Wi-Fi in the rooms and parking on site.

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Luxury Hotels in Florence

We recommend Comfort Suites I-95 {rating: 8.4/10} for 107US$ per night. This top property offers a business centre, housekeeping service, and 24 hour front desk assistance on site. Another good deal is Hotel, Tapestry Collection By Hilton (rating: 8.4/10) with children's menu, housekeeping, and a spa area on site. It's set 550 metres from the city centre.

Luxury Hotels in Florence FAQ
1. What are some of the top luxury hotels in Florence?
Florence offers a range of luxury accommodations, including Country Inn & Suites By Radisson, Howard Johnson By Wyndham Florence, Staybridge Suites - Florence Center, La Quinta By Wyndham Florence, and Days Inn By Wyndham Florence Near Civic Center. Whether you're looking for a boutique hotel, a historic property, or a modern retreat, Florence has something to suit every traveler's preference and budget.
2. When is the best time to visit Florence for a luxury hotel experience?
The best time to visit Florence for a luxury hotel experience is during the spring and fall seasons when the weather is mild and the city is less crowded. This allows for a more relaxed and enjoyable stay at upscale accommodations, where you can take advantage of special offers and packages while exploring the city's renowned art and cultural attractions.
3. What amenities can I expect at luxury hotels in Florence?
Luxury hotels in Florence offer a range of amenities to ensure a comfortable and memorable stay. From luxurious spa services and fine dining options to rooftop terraces with panoramic views and concierge services, guests can expect a high level of service and attention to detail at properties like Country Inn & Suites By Radisson, Howard Johnson By Wyndham Florence, Staybridge Suites - Florence Center, La Quinta By Wyndham Florence, and Days Inn By Wyndham Florence Near Civic Center.

Location

Florence, South Carolina, United States, 29501

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